Ashley Woodfin

2013         M.Sc. in Bioinformatics, University of Oregon, Eugene, Oregon, USA
2012         B.Sc. in Molecular Biology, University of Oregon, Eugene, Oregon, USA
October 2015 - Present         Bioinformatician in Alexander Stark group, IMP, Vienna, Austria
October 2013 - September 2015         Bioinformatician in Ali Shilatifard laboratory, Feinberg School of Medicine Northwestern University, Chicago, USA
January  - September 2013         Bioinformatics Intern in Rong Li laboratory, Stowers Institute, Kansas City, USA
Research Interests

Using Next-Generation Sequencing (NGS) data analysis (STARR-seq, ChiP-seq, RNA-seq, GRO-seq) to assay transcriptional regulation.

  • Muerdter F*, Boryń ŁM*, Woodfin AR**, Neumayr C**, Rath M, Zabidi MA, Pagani M, Haberle V, Kazmar T, Catarino RR, Schernhuber K, Arnold CD, Stark A. Resolving systematic errors in widely-used enhancer activity assays in human cells enables genome-wide functional enhancer characterization. bioRxiv, 2017. July 17. (abstract)

  • Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, James CD, Shilatifard A. Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas. Nature Medicine, 2017. Feb. (abstract)

  • Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. Cell, 2017. Jan 12;168:1-14. (abstract)

  • Rickels R, Hu D, Collings CK, Woodfin AR, Piunti A, Mohan M, Herz HM, Kvon E, Shilatifard A. An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Molecular Cell, 2016. Jul 21;63(2):318-28. (abstract)

  • Luo Z, Lin C, Woodfin, AR, Bartom ET, Gao X, Smith ER, Shilatifard A. Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity. Genes and Development, 2016. Jan 1;30(1):92-101. (abstract)

  • Liang K, Woodfin, AR, Slaughter BD, Unruh JR, Box AC, Rickels RA, Gao X, Haug JS, Jaspersen SL, Shilatifard A. Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis. Molecular Cell, 2015. Nov 5;60(3):435-45. (abstract)

  • Chen FX, Woodfin, AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell, 2015. Aug 27;162(5):1003-15. (abstract)

  • Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin, AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A. Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation. Genes and Development, 2014. Jan 15;28(2):115-20. (abstract)