Congratulations to Leo and all co-authors on their newest preprint! They show that promoter classes with distinct functions and initiation patterns function via pre-initiation complexes that display different compositions and dependencies.
Read Leo’s Tweetorial.
Serebreni L, Pleyer LM, Haberle V, Hendy O, Vlasova A, Loubiere V, Nemčko F, Bergauer K, Roitinger E, Mechtler K, Stark A. Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns. bioRxiv, October 2022.
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