Haberle V*, Arnold CD*, Pagani M, Rath M, Schernhuber K, Stark A. Transcriptional cofactors display specificity for distinct types of core promoters. Nature 2019, May 15. Pubmed 31092928

FLY (D. melanogaster) Kc167 CELLS COF-STAP-seq

• Tracks on the UCSC Genome Browser

• Processed data tables (also on NCBI GEO (GSE116197))

  List of 72,000 CP candidates included in the STAP-seq library [17M]
  Unique tagcounts (not normalized) for all CP candidates - 3 replicates per COF [6.1M]
  Normalized tagcounts (normalized to spike-in) for all CP candidates - merged replicates per COF [8.9M]

• Raw sequencing data (also on NCBI GEO (GSE116197)) Note that the first 10 nucleotides of the read 1 are UMI (unique molecular identifier) and should be removed before mapping (but kept for correct counting of the unique initiation events after mapping).

  P65
  P65 Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [395M]
  P65 Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [417M]
  P65 Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [661M]
  P65 Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [707M]
  P65 Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [337M]
  P65 Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [354M]

  MED25
  MED25 Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [439M]
  MED25 Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [464M]
  MED25 Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [416M]
  MED25 Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [444M]
  MED25 Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [541M]
  MED25 Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [570M]

  P300 (Nej)
  P300 Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [281M]
  P300 Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [296M]
  P300 Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [229M]
  P300 Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [242M]
  P300 Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [420M]
  P300 Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [444M]

  Lpt
  Lpt Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [238M]
  Lpt Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [249M]
  Lpt Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [140M]
  Lpt Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [148M]
  Lpt Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [104M]
  Lpt Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [111M]

  Gfzf
  Gfzf Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [70M]
  Gfzf Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [82M]
  Gfzf Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [94M]
  Gfzf Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [108M]
  Gfzf Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [26M]
  Gfzf Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [30M]

  Chro
  Chro Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [92M]
  Chro Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [111M]
  Chro Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [163M]
  Chro Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [195M]
  Chro Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [97M]
  Chro Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [117M]

  Mof
  Mof Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [54M]
  Mof Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [57M]
  Mof Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [120M]
  Mof Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [126M]
  Mof Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [40M]
  Mof Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [41M]

  GFP
  GFP Kc167 cells COF-STAP-seq Rep1, paired-end read 1 [17M]
  GFP Kc167 cells COF-STAP-seq Rep1, paired-end read 2 [18M]
  GFP Kc167 cells COF-STAP-seq Rep2, paired-end read 1 [31M]
  GFP Kc167 cells COF-STAP-seq Rep2, paired-end read 2 [32M]
  GFP Kc167 cells COF-STAP-seq Rep3, paired-end read 1 [11M]
  GFP Kc167 cells COF-STAP-seq Rep3, paired-end read 2 [11M]

  input CP library
  Input 4xUAS CP library, paired-end read 1 [226M]
  Input 4xUAS CP library, paired-end read 2 [220M]