Haberle V*, Arnold CD*, Pagani M, Rath M, Schernhuber K, Stark A. Transcriptional cofactors display specificity for distinct types of core promoters. Nature 2019, May 15. Pubmed 31092928

FLY (D. melanogaster) OSC CELLS COF-STAP-seq

• Tracks on the UCSC Genome Browser

• Processed data tables (also on NCBI GEO (GSE116197))

  List of 72,000 CP candidates included in the STAP-seq library [17M]
  Unique tagcounts (not normalized) for all CP candidates - 3 replicates per COF [6.2M]
  Normalized tagcounts (normalized to spike-in) for all CP candidates - merged replicates per COF [11M]

• Raw sequencing data (also on NCBI GEO (GSE116197))
  Note that the first 10 nucleotides of the read 1 are UMI (unique molecular identifier) and should be removed before mapping (but kept for correct counting of the unique initiation events after mapping).

  P65
  P65 OSC cells COF-STAP-seq Rep1, paired-end read 1 [699M]
  P65 OSC cells COF-STAP-seq Rep1, paired-end read 2 [752M]
  P65 OSC cells COF-STAP-seq Rep2, paired-end read 1 [827M]
  P65 OSC cells COF-STAP-seq Rep2, paired-end read 2 [932M]
  P65 OSC cells COF-STAP-seq Rep3, paired-end read 1 [763M]
  P65 OSC cells COF-STAP-seq Rep3, paired-end read 2 [815M]

  MED25
  MED25 OSC cells COF-STAP-seq Rep1, paired-end read 1 [699M]
  MED25 OSC cells COF-STAP-seq Rep1, paired-end read 2 [737M]
  MED25 OSC cells COF-STAP-seq Rep2, paired-end read 1 [516M]
  MED25 OSC cells COF-STAP-seq Rep2, paired-end read 2 [578M]
  MED25 OSC cells COF-STAP-seq Rep3, paired-end read 1 [711M]
  MED25 OSC cells COF-STAP-seq Rep3, paired-end read 2 [751M]

  P300 (Nej)
  P300 OSC cells COF-STAP-seq Rep1, paired-end read 1 [107M]
  P300 OSC cells COF-STAP-seq Rep1, paired-end read 2 [113M]
  P300 OSC cells COF-STAP-seq Rep2, paired-end read 1 [54M]
  P300 OSC cells COF-STAP-seq Rep2, paired-end read 2 [60M]
  P300 OSC cells COF-STAP-seq Rep3, paired-end read 1 [67M]
  P300 OSC cells COF-STAP-seq Rep3, paired-end read 2 [70M]

  Lpt
  Lpt OSC cells COF-STAP-seq Rep1, paired-end read 1 [161M]
  Lpt OSC cells COF-STAP-seq Rep1, paired-end read 2 [170M]
  Lpt OSC cells COF-STAP-seq Rep2, paired-end read 1 [141M]
  Lpt OSC cells COF-STAP-seq Rep2, paired-end read 2 [156M]
  Lpt OSC cells COF-STAP-seq Rep3, paired-end read 1 [158M]
  Lpt OSC cells COF-STAP-seq Rep3, paired-end read 2 [166M]

  Gfzf
  Gfzf OSC cells COF-STAP-seq Rep1, paired-end read 1 [153M]
  Gfzf OSC cells COF-STAP-seq Rep1, paired-end read 2 [175M]
  Gfzf OSC cells COF-STAP-seq Rep2, paired-end read 1 [107M]
  Gfzf OSC cells COF-STAP-seq Rep2, paired-end read 2 [130M]
  Gfzf OSC cells COF-STAP-seq Rep3, paired-end read 1 [108M]
  Gfzf OSC cells COF-STAP-seq Rep3, paired-end read 2 [124M]

  Chro
  Chro OSC cells COF-STAP-seq Rep1, paired-end read 1 [116M]
  Chro OSC cells COF-STAP-seq Rep1, paired-end read 2 [136M]
  Chro OSC cells COF-STAP-seq Rep2, paired-end read 1 [136M]
  Chro OSC cells COF-STAP-seq Rep2, paired-end read 2 [169M]
  Chro OSC cells COF-STAP-seq Rep3, paired-end read 1 [102M]
  Chro OSC cells COF-STAP-seq Rep3, paired-end read 2 [119M]

  Mof
  Mof OSC cells COF-STAP-seq Rep1, paired-end read 1 [36M]
  Mof OSC cells COF-STAP-seq Rep1, paired-end read 2 [38M]
  Mof OSC cells COF-STAP-seq Rep2, paired-end read 1 [72M]
  Mof OSC cells COF-STAP-seq Rep2, paired-end read 2 [83M]
  Mof OSC cells COF-STAP-seq Rep3, paired-end read 1 [42M]
  Mof OSC cells COF-STAP-seq Rep3, paired-end read 2 [44M]

  GFP
  GFP OSC cells COF-STAP-seq Rep1, paired-end read 1 [14M]
  GFP OSC cells COF-STAP-seq Rep1, paired-end read 2 [15M]
  GFP OSC cells COF-STAP-seq Rep2, paired-end read 1 [9.0M]
  GFP OSC cells COF-STAP-seq Rep2, paired-end read 2 [9.8M]
  GFP OSC cells COF-STAP-seq Rep3, paired-end read 1 [7.3M]
  GFP OSC cells COF-STAP-seq Rep3, paired-end read 2 [7.5M]

  input CP library
  Input 4xUAS CP library, paired-end read 1 [226M]
  Input 4xUAS CP library, paired-end read 2 [220M]